Seminars

A seminar or talk, either on campus or off campus

Masters Thesis Presentation

Masters Thesis Defense

Department of Physics

Photo- and Bio-Physical Characterization of Novel Lipophilic Fluorescent Dyes
For Multicolor Neurotracing and Transcellular Lipid Diusion Measurements

by
Jeffrey Tonniges

Abstract:

Lipophilic Fluorescent dyes are used to trace neuronal connections and probe cellular activities by insertion into and lateral diusion within cell membranes. The photophysical and biophysical properties of two sets of lipophilic Fluorescent dyes were characterized to study: 1) how to increase the number of distinct colors in a single specimen for neurotracing, and 2) how the hydrocarbon chain length aects the mechanism for lipid diusion in living cells. To address these inquiries, fluorescence spectroscopy measurements of a multicolored dye set and diusion measurements in cultured cells of a set of dyes with various hydrocarbon chain lengths were performed. Two-photon excitation action cross sections for the multicolored dye set and their use in designing multicolor imaging protocols will be discussed. Transcellular diusion and FRAP measurements of the chain-variant dye set will be presented and the role of the hydrocarbon chain length on lipid diusion will be explored.

Location
Rigge Science G05
Date of Event
Contact info
Dr. Michael Nichols

Physics Department Seminar 04-09-2010

Professor David W. McLaughlin, Professor of Mathematics and Neural Sciences, Provost at NYU, and a 1966 Creighton graduate who was one of the first to complete our Bachelor of Science in Physics degree, will be presenting the Physics Seminar this week on Friday, April 9th, at the usual time: 12:30 p.m.  Dr. McLaughlin will be here to receive this year's Alumni Merit Award from the College of Arts and Sciences. His talk is entitled

“Modeling the Dynamics of the Cortex: Spatio-Temporal Cortical Activity”

Location
HL G59
Date of Event
Contact info
Dr. Jack Gabel

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